Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	GDF11	HGNC:4216 (HGNC) 10220 (Entrez Gene) 603936 (OMIM) GDF11 (Alliance of Genome Resources)	Chr12 q13.2	Chr12:55743122-55757264 (+) GRCh38	vertebral hypersegmentation and orofacial anomalies	O95390 (UniProt | EBI) NM_005811 (RefSeq)
mouse	Gdf11	MGI:1338027 (MGI) 14561 (Entrez Gene) Gene Tree Gdf11 (Alliance of Genome Resources)	Chr10 77.18 cM	Chr10:128718164-128727587 (-) GRCm39		ENSMUSG00000025352 (Ensembl Gene Model) ENSMUSP00000026408 (Ensembl) ENSMUST00000026408 (Ensembl)
rat	Gdf11	RGD:2673 (Rat Genome Database) 29454 (Entrez Gene) Gdf11 (Alliance of Genome Resources)	Chr7 q11			Q9Z217 (UniProt | EBI) NM_017203 (RefSeq)
zebrafish	gdf11	ZDB-GENE-040427-2 (Zebrafish Model Organism Database) 406247 (Entrez Gene) gdf11 (Alliance of Genome Resources)	Chr11			NP_998140 (RefSeq) NM_212975 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.