Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	LCK	HGNC:6524 (HGNC) 3932 (Entrez Gene) 153390 (OMIM) LCK (Alliance of Genome Resources)	Chr1 p35.2	Chr1:32251244-32286165 (+) GRCh38	immunodeficiency 22	P06239 (UniProt | EBI) NM_001330468 (RefSeq)
mouse	Lck	MGI:96756 (MGI) 16818 (Entrez Gene) Gene Tree Lck (Alliance of Genome Resources)	Chr4 63.26 cM	Chr4:129442142-129467415 (-) GRCm39		16818 (NCBI Gene Model) P06240 (UniProt | EBI) NM_010693 (RefSeq)
rat	Lck	RGD:2994 (Rat Genome Database) 313050 (Entrez Gene) Lck (Alliance of Genome Resources)	Chr5 q36			Q01621 (UniProt | EBI) NM_001415870 (RefSeq)
zebrafish	lck	ZDB-GENE-040617-1 (Zebrafish Model Organism Database) 414333 (Entrez Gene) lck (Alliance of Genome Resources)	Chr17			NP_001035418 (RefSeq) NM_001040328 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.