Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CRYBA1	HGNC:2394 (HGNC) 1411 (Entrez Gene) 123610 (OMIM) CRYBA1 (Alliance of Genome Resources)	Chr17 q11.2	Chr17:29246859-29254494 (+) GRCh38	cataract cataract 10 multiple types	P05813 (UniProt | EBI) NM_005208 (RefSeq)
mouse	Cryba1	MGI:88518 (MGI) 12957 (Entrez Gene) Gene Tree Cryba1 (Alliance of Genome Resources)	Chr11 46.74 cM	Chr11:77609441-77616109 (-) GRCm39	age related macular degeneration 1 cataract 10 multiple types	ENSMUSG00000000724 (Ensembl Gene Model) ENSMUSP00000077693 (Ensembl) ENSMUST00000078623 (Ensembl)
rat	Cryba1	RGD:2415 (Rat Genome Database) 25583 (Entrez Gene) Cryba1 (Alliance of Genome Resources)	Chr10 q24			P14881 (UniProt | EBI) NM_013056 (RefSeq)
zebrafish	cryba1a	ZDB-GENE-040718-107 (Zebrafish Model Organism Database) 436683 (Entrez Gene) cryba1a (Alliance of Genome Resources)	Chr15			NP_001002410 (RefSeq) NM_001002410 (RefSeq)
	cryba1b	ZDB-GENE-040718-326 (Zebrafish Model Organism Database) 436859 (Entrez Gene) cryba1b (Alliance of Genome Resources)	Chr21			NP_001002586 (RefSeq) NM_001002586 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.