Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SDHD	HGNC:10683 (HGNC) 6392 (Entrez Gene) 602690 (OMIM) SDHD (Alliance of Genome Resources)	Chr11 q23.1	Chr11:112086824-112120016 (+) GRCh38	Carney-Stratakis syndrome mitochondrial complex II deficiency paraganglioma	O14521 (UniProt | EBI) NM_001276503 (RefSeq)
mouse	Sdhd	MGI:1914175 (MGI) 66925 (Entrez Gene) Gene Tree Sdhd (Alliance of Genome Resources)	Chr9 27.75 cM	Chr9:50507657-50515112 (-) GRCm39		ENSMUSG00000000171 (Ensembl Gene Model) ENSMUSP00000000175 (Ensembl) ENSMUST00000000175 (Ensembl)
rat	Sdhd	RGD:735231 (Rat Genome Database) 363061 (Entrez Gene) Sdhd (Alliance of Genome Resources)	Chr8 q23			Q6PCT8 (UniProt | EBI) NM_198788 (RefSeq)
zebrafish	sdhda	ZDB-GENE-040718-192 (Zebrafish Model Organism Database) 436762 (Entrez Gene) sdhda (Alliance of Genome Resources)	Chr5			Q6DGM2 (UniProt | EBI) NM_001002489 (RefSeq)
	sdhdb	ZDB-GENE-040822-17 (Zebrafish Model Organism Database) 445500 (Entrez Gene) sdhdb (Alliance of Genome Resources)	Chr15			Q68FN7 (UniProt | EBI) NM_001004004 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.