Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PCCA	HGNC:8653 (HGNC) 5095 (Entrez Gene) 232000 (OMIM) PCCA (Alliance of Genome Resources)	Chr13 q32.3	Chr13:100089015-100530437 (+) GRCh38	amino acid metabolic disorder propionic acidemia	P05165 (UniProt | EBI) NM_001178004 (RefSeq)
mouse	Pcca	MGI:97499 (MGI) 110821 (Entrez Gene) Gene Tree Pcca (Alliance of Genome Resources)	Chr14 65.99 cM	Chr14:122771736-123128512 (+) GRCm39	propionic acidemia	ENSMUSG00000041650 (Ensembl Gene Model) ENSMUSP00000038763 (Ensembl) ENSMUST00000038374 (Ensembl)
rat	Pcca	RGD:3264 (Rat Genome Database) 687008 (Entrez Gene) Pcca (Alliance of Genome Resources)	Chr15			P14882 (UniProt | EBI) NM_019330 (RefSeq)
zebrafish	pcca	ZDB-GENE-040718-246 (Zebrafish Model Organism Database) 437019 (Entrez Gene) pcca (Alliance of Genome Resources)	Chr1			NP_001002746 (RefSeq) NM_001002746 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.