Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	KDM6B	HGNC:29012 (HGNC) 23135 (Entrez Gene) 611577 (OMIM) KDM6B (Alliance of Genome Resources)	Chr17 p13.1	Chr17:7834217-7854796 (+) GRCh38	Stolerman neurodevelopmental syndrome	O15054 (UniProt | EBI) NM_001080424 (RefSeq)
mouse	Kdm6b	MGI:2448492 (MGI) 216850 (Entrez Gene) Gene Tree Kdm6b (Alliance of Genome Resources)	Chr11 42.6 cM	Chr11:69289334-69304501 (-) GRCm39		ENSMUSG00000018476 (Ensembl Gene Model) ENSMUSP00000091620 (Ensembl) ENSMUST00000094077 (Ensembl)
rat	Kdm6b	RGD:1307629 (Rat Genome Database) 363630 (Entrez Gene) Kdm6b (Alliance of Genome Resources)	Chr10 q24			NP_001388879 (RefSeq) NM_001401950 (RefSeq)
zebrafish	kdm6ba	ZDB-GENE-091005-1 (Zebrafish Model Organism Database) 556678 (Entrez Gene) kdm6ba (Alliance of Genome Resources)	Chr7			XP_068078683 (RefSeq)
	kdm6bb	ZDB-GENE-040724-166 (Zebrafish Model Organism Database) 563644 (Entrez Gene) kdm6bb (Alliance of Genome Resources)	Chr10			NP_001025349 (RefSeq) NM_001030178 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.