Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NAT1	HGNC:7645 (HGNC) 9 (Entrez Gene) 108345 (OMIM) NAT1 (Alliance of Genome Resources)	Chr8 p22	Chr8:18170467-18223689 (+) GRCh38	adenocarcinoma allergic contact dermatitis lung non-small cell carcinoma occupational dermatitis pancreatic cancer prostate cancer	P18440 (UniProt | EBI) NM_001291962 (RefSeq)
	NAT2	HGNC:7646 (HGNC) 10 (Entrez Gene) 612182 (OMIM) NAT2 (Alliance of Genome Resources)	Chr8 p22	Chr8:18386301-18401218 (+) GRCh38	acute lymphoblastic leukemia acute myeloid leukemia allergic contact dermatitis asthma atopic dermatitis Behcet's disease cholangiocarcinoma chronic obstructive pulmonary disease diabetes mellitus laryngeal squamous cell carcinoma leukemia lung cancer lung disease malignant mesothelioma occupational dermatitis oral mucosa leukoplakia pancreatic cancer Parkinson's disease progressive supranuclear palsy prostate cancer psoriasis pulmonary tuberculosis senile cataract systemic lupus erythematosus systemic scleroderma transitional cell carcinoma urinary bladder cancer	P11245 (UniProt | EBI) NM_000015 (RefSeq)
mouse	Nat3	MGI:102537 (MGI) 17962 (Entrez Gene) Gene Tree Nat3 (Alliance of Genome Resources)	Chr8 33.39 cM	Chr8:67976506-68001279 (+) GRCm39		17962 (NCBI Gene Model) P50296 (UniProt | EBI) NM_008674 (RefSeq)
rat	Nat3	RGD:1307575 (Rat Genome Database) 290681 (Entrez Gene) Nat3 (Alliance of Genome Resources)	Chr16 p14			NP_001013070 (RefSeq) NM_001013052 (RefSeq)
zebrafish	si:dkey-78a14.4	ZDB-GENE-110408-8 (Zebrafish Model Organism Database) 794381 (Entrez Gene) si:dkey-78a14.4 (Alliance of Genome Resources)	Chr7			XP_068078800 (RefSeq)
	zgc:101040	ZDB-GENE-040801-107 (Zebrafish Model Organism Database) 445194 (Entrez Gene) zgc:101040 (Alliance of Genome Resources)	Chr18			NP_001003588 (RefSeq) NM_001003588 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.