Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SGMS2	HGNC:28395 (HGNC) 166929 (Entrez Gene) 611574 (OMIM) SGMS2 (Alliance of Genome Resources)	Chr4 q25	Chr4:107824563-107915047 (+) GRCh38	calvarial doughnut lesions with bone fragility	Q8NHU3 (UniProt | EBI) NM_001136258 (RefSeq)
mouse	Sgms2	MGI:1921692 (MGI) 74442 (Entrez Gene) Gene Tree Sgms2 (Alliance of Genome Resources)	Chr3 60.91 cM	Chr3:131112634-131197172 (-) GRCm39		ENSMUSG00000050931 (Ensembl Gene Model) ENSMUSP00000087713 (Ensembl) ENSMUST00000090246 (Ensembl)
rat	Sgms2	RGD:1305778 (Rat Genome Database) 310849 (Entrez Gene) Sgms2 (Alliance of Genome Resources)	Chr2 q43			Q4JM44 (UniProt | EBI) NM_001014043 (RefSeq)
zebrafish	sgms2a	ZDB-GENE-070730-2 (Zebrafish Model Organism Database) 556193 (Entrez Gene) sgms2a (Alliance of Genome Resources)	Chr1			NP_001139035 (RefSeq) NM_001145563 (RefSeq)
	sgms2b	ZDB-GENE-040801-162 (Zebrafish Model Organism Database) 445247 (Entrez Gene) sgms2b (Alliance of Genome Resources)	Chr23			NP_001003641 (RefSeq) NM_001003641 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.