Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PON3	HGNC:9206 (HGNC) 5446 (Entrez Gene) 602720 (OMIM) PON3 (Alliance of Genome Resources)	Chr7 q21.3	Chr7:95359872-95396375 (-) GRCh38	Alzheimer's disease amyotrophic lateral sclerosis atherosclerosis	Q15166 (UniProt | EBI) NM_000940 (RefSeq)
mouse	Pon3	MGI:106686 (MGI) 269823 (Entrez Gene) Gene Tree Pon3 (Alliance of Genome Resources)	Chr6 1.99 cM	Chr6:5220852-5256286 (-) GRCm39		ENSMUSG00000029759 (Ensembl Gene Model) ENSMUSP00000031773 (Ensembl) ENSMUST00000031773 (Ensembl)
rat	Pon3	RGD:1302965 (Rat Genome Database) 312086 (Entrez Gene) Pon3 (Alliance of Genome Resources)	Chr4 q21			Q68FP2 (UniProt | EBI) NM_001004086 (RefSeq)
zebrafish	pon1	ZDB-GENE-040912-6 (Zebrafish Model Organism Database) 447803 (Entrez Gene) pon1 (Alliance of Genome Resources)	Chr16			NP_001004542 (RefSeq) NM_001004542 (RefSeq)
	pon3.1	ZDB-GENE-050522-353 (Zebrafish Model Organism Database) 554122 (Entrez Gene) pon3.1 (Alliance of Genome Resources)	Chr16			NP_001019588 (RefSeq) NM_001024417 (RefSeq)
	pon3.2	ZDB-GENE-071004-70 (Zebrafish Model Organism Database) 568655 (Entrez Gene) pon3.2 (Alliance of Genome Resources)	Chr16			NP_001098592 (RefSeq) NM_001105122 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.