Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CAPN3	HGNC:1480 (HGNC) 825 (Entrez Gene) 114240 (OMIM) CAPN3 (Alliance of Genome Resources)	Chr15 q15.1	Chr15:42359498-42412949 (+) GRCh38	autosomal dominant limb-girdle muscular dystrophy autosomal recessive limb-girdle muscular dystrophy type 2A muscular dystrophy	P20807 (UniProt | EBI) NM_173087 (RefSeq)
mouse	Capn3	MGI:107437 (MGI) 12335 (Entrez Gene) Gene Tree Capn3 (Alliance of Genome Resources)	Chr2 60.31 cM	Chr2:120294074-120335400 (+) GRCm39	autosomal recessive limb-girdle muscular dystrophy type 2A	12335 (NCBI Gene Model) Q64691 (UniProt | EBI) NM_007601 (RefSeq)
rat	Capn3	RGD:2269 (Rat Genome Database) 29155 (Entrez Gene) Capn3 (Alliance of Genome Resources)	Chr3 q35			P16259 (UniProt | EBI) NM_017117 (RefSeq)
zebrafish	capn3a	ZDB-GENE-040912-97 (Zebrafish Model Organism Database) 447832 (Entrez Gene) capn3a (Alliance of Genome Resources)	Chr17			NP_001004571 (RefSeq) NM_001004571 (RefSeq)
	capn3b	ZDB-GENE-041001-149 (Zebrafish Model Organism Database) 100034405 (Entrez Gene) capn3b (Alliance of Genome Resources)	Chr20			NP_001230250 (RefSeq) NM_001243321 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.