Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MTHFD1L	HGNC:21055 (HGNC) 25902 (Entrez Gene) 611427 (OMIM) MTHFD1L (Alliance of Genome Resources)	Chr6 q25.1	Chr6:150865679-151101887 (+) GRCh38	neural tube defect	Q6UB35 (UniProt | EBI) NM_001350489 (RefSeq)
mouse	Mthfd1l	MGI:1924836 (MGI) 270685 (Entrez Gene) Gene Tree Mthfd1l (Alliance of Genome Resources)	Chr10 2.06 cM	Chr10:3923118-4117081 (+) GRCm39	neural tube defect	ENSMUSG00000040675 (Ensembl Gene Model) ENSMUSP00000036178 (Ensembl) ENSMUST00000043735 (Ensembl)
rat	Mthfd1l	RGD:1307311 (Rat Genome Database) 361472 (Entrez Gene) Mthfd1l (Alliance of Genome Resources)	Chr1 p11-q11			NP_001101932 (RefSeq) NM_001108462 (RefSeq)
zebrafish	mthfd1l	ZDB-GENE-041001-133 (Zebrafish Model Organism Database) 100034522 (Entrez Gene) mthfd1l (Alliance of Genome Resources)	Chr20			NP_001229925 (RefSeq) NM_001242996 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.