Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MAP2K2	HGNC:6842 (HGNC) 5605 (Entrez Gene) 601263 (OMIM) MAP2K2 (Alliance of Genome Resources)	Chr19 p13.3	Chr19:4090321-4124122 (-) GRCh38	cardiofaciocutaneous syndrome 4 small intestine adenocarcinoma	P36507 (UniProt | EBI) NM_030662 (RefSeq)
mouse	Map2k2	MGI:1346867 (MGI) 26396 (Entrez Gene) Gene Tree Map2k2 (Alliance of Genome Resources)	Chr10 39.72 cM	Chr10:80941749-80960531 (+) GRCm39		26396 (NCBI Gene Model) Q63932 (UniProt | EBI) NM_001428901 (RefSeq)
rat	Map2k2	RGD:61888 (Rat Genome Database) 58960 (Entrez Gene) Map2k2 (Alliance of Genome Resources)	Chr7 q11			P36506 (UniProt | EBI) NM_133283 (RefSeq)
zebrafish	map2k2a	ZDB-GENE-041027-1 (Zebrafish Model Organism Database) 563181 (Entrez Gene) map2k2a (Alliance of Genome Resources)	Chr22			NP_001032468 (RefSeq) NM_001037391 (RefSeq)
	map2k2b	ZDB-GENE-080219-34 (Zebrafish Model Organism Database) 100002225 (Entrez Gene) map2k2b (Alliance of Genome Resources)	Chr2			NP_001121753 (RefSeq) NM_001128281 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.