Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	DDX11	HGNC:2736 (HGNC) 1663 (Entrez Gene) 601150 (OMIM) DDX11 (Alliance of Genome Resources)	Chr12 p11.21	Chr12:31073860-31104799 (+) GRCh38	Warsaw breakage syndrome	Q96FC9 (UniProt | EBI) NM_030653 (RefSeq)
	DDX11L8	HGNC:37101 (HGNC) 100302090 (Entrez Gene) DDX11L8 (Alliance of Genome Resources)	Chr	Chr12:12310-14526 (+) GRCh38		A8MPP1 (UniProt | EBI)
	DDX12P	HGNC:2737 (HGNC) 440081 (Entrez Gene) DDX12P (Alliance of Genome Resources)	Chr12 p13.31	Chr12:9417691-9448229 (-) GRCh38		Q92771 (UniProt | EBI) NM_004400 (RefSeq)
mouse	Ddx11	MGI:2443590 (MGI) 320209 (Entrez Gene) Gene Tree Ddx11 (Alliance of Genome Resources)	Chr17 35.26 cM	Chr17:66430515-66459169 (+) GRCm39		ENSMUSG00000035842 (Ensembl Gene Model) ENSMUSP00000153436 (Ensembl) ENSMUST00000224497 (Ensembl)
rat	Ddx11	RGD:1306675 (Rat Genome Database) 316767 (Entrez Gene) Ddx11 (Alliance of Genome Resources)	Chr9 q37			NP_001414530 (RefSeq) NM_001427601 (RefSeq)
zebrafish	ddx11	ZDB-GENE-041114-191 (Zebrafish Model Organism Database) 492353 (Entrez Gene) ddx11 (Alliance of Genome Resources)	Chr18			F1R345 (UniProt | EBI) NM_001007319 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.