Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PUS1	HGNC:15508 (HGNC) 80324 (Entrez Gene) 608109 (OMIM) PUS1 (Alliance of Genome Resources)	Chr12 q24.33	Chr12:131929200-131945896 (+) GRCh38	myopathy, lactic acidosis, and sideroblastic anemia 1	Q9Y606 (UniProt | EBI) NM_001002019 (RefSeq)
mouse	Pus1	MGI:1929237 (MGI) 56361 (Entrez Gene) Gene Tree Pus1 (Alliance of Genome Resources)	Chr5 53.7 cM	Chr5:110921533-110928523 (-) GRCm39	myopathy, lactic acidosis, and sideroblastic anemia	56361 (NCBI Gene Model) Q9WU56 (UniProt | EBI) NM_001025561 (RefSeq)
rat	Pus1	RGD:1311871 (Rat Genome Database) 304567 (Entrez Gene) Pus1 (Alliance of Genome Resources)	Chr12 q16			Q4KM92 (UniProt | EBI) NM_001025563 (RefSeq)
zebrafish	pus1	ZDB-GENE-041212-26 (Zebrafish Model Organism Database) 494060 (Entrez Gene) pus1 (Alliance of Genome Resources)	Chr21			NP_001008603 (RefSeq) NM_001008603 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.