Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	FGF23	HGNC:3680 (HGNC) 8074 (Entrez Gene) 605380 (OMIM) FGF23 (Alliance of Genome Resources)	Chr12 p13.32	Chr12:4368227-4379712 (-) GRCh38	autosomal dominant hypophosphatemic rickets	Q9GZV9 (UniProt | EBI) NM_020638 (RefSeq)
mouse	Fgf23	MGI:1891427 (MGI) 64654 (Entrez Gene) Gene Tree Fgf23 (Alliance of Genome Resources)	Chr6 61.92 cM	Chr6:127049865-127058371 (+) GRCm39	autosomal dominant hypophosphatemic rickets	ENSMUSG00000000182 (Ensembl Gene Model) ENSMUSP00000000186 (Ensembl) ENSMUST00000000186 (Ensembl)
rat	Fgf23	RGD:620178 (Rat Genome Database) 170583 (Entrez Gene) Fgf23 (Alliance of Genome Resources)	Chr4 q42			Q8VI82 (UniProt | EBI) NM_130754 (RefSeq)
zebrafish	fgf23	ZDB-GENE-050201-4 (Zebrafish Model Organism Database) 494456 (Entrez Gene) fgf23 (Alliance of Genome Resources)	Chr4			NP_001009564 (RefSeq) NM_001009564 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.