Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SPEN	HGNC:17575 (HGNC) 23013 (Entrez Gene) 613484 (OMIM) SPEN (Alliance of Genome Resources)	Chr1 p36.21-p36.13	Chr1:15836095-15940456 (+) GRCh38	esophagus squamous cell carcinoma	Q96T58 (UniProt | EBI) NM_015001 (RefSeq)
mouse	Spen	MGI:1891706 (MGI) 56381 (Entrez Gene) Gene Tree Spen (Alliance of Genome Resources)	Chr4 74.26 cM	Chr4:141195201-141265908 (-) GRCm39		ENSMUSG00000040761 (Ensembl Gene Model) ENSMUSP00000101412 (Ensembl) ENSMUST00000105786 (Ensembl)
rat	Spen	RGD:1589867 (Rat Genome Database) 690911 (Entrez Gene) Spen (Alliance of Genome Resources)	Chr5 q36			NP_001382030 (RefSeq) NM_001395101 (RefSeq)
zebrafish	spen	ZDB-GENE-050309-70 (Zebrafish Model Organism Database) 503940 (Entrez Gene) spen (Alliance of Genome Resources)	Chr23			XP_021329363 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.