Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HSPA1A	HGNC:5232 (HGNC) 3303 (Entrez Gene) 140550 (OMIM) HSPA1A (Alliance of Genome Resources)	Chr6 p21.33	Chr6:31815543-31817946 (+) GRCh38	Alzheimer's disease atherosclerosis cystic fibrosis Kawasaki disease major depressive disorder Meniere's disease paranoid schizophrenia Parkinsonism schizophrenia systemic lupus erythematosus urinary bladder cancer vascular dementia vitiligo	P0DMV8 (UniProt | EBI) NM_005345 (RefSeq)
	HSPA1B	HGNC:5233 (HGNC) 3304 (Entrez Gene) 603012 (OMIM) HSPA1B (Alliance of Genome Resources)	Chr6 p21.33	Chr6:31827738-31830254 (+) GRCh38	Alzheimer's disease brain ischemia CAKUT familial hyperlipidemia obesity schizophrenia senile cataract toxic shock syndrome type 2 diabetes mellitus urinary tract infection	P0DMV9 (UniProt | EBI) NM_005346 (RefSeq)
mouse	Hspa1a	MGI:96244 (MGI) 193740 (Entrez Gene) Gene Tree Hspa1a (Alliance of Genome Resources)	Chr17 18.51 cM	Chr17:35188335-35191132 (-) GRCm39		193740 (NCBI Gene Model) Q61696 (UniProt | EBI) NM_010479 (RefSeq)
rat	Hspa1a	RGD:2840 (Rat Genome Database) 24472 (Entrez Gene) Hspa1a (Alliance of Genome Resources)	Chr20 p12			P0DMW0 (UniProt | EBI) NM_031971 (RefSeq)
	Hspa1b	RGD:1593284 (Rat Genome Database) 108348108 (Entrez Gene) Hspa1b (Alliance of Genome Resources)	Chr20			P0DMW1 (UniProt | EBI) NM_001329896 (RefSeq)
zebrafish	hsp70.1	ZDB-GENE-990415-91 (Zebrafish Model Organism Database) 100126123 (Entrez Gene) hsp70.1 (Alliance of Genome Resources)	Chr3			NP_001349288 (RefSeq) NM_001362359 (RefSeq)
	hsp70.2	ZDB-GENE-110405-1 (Zebrafish Model Organism Database) 100535101 (Entrez Gene) hsp70.2 (Alliance of Genome Resources)	Chr3			NP_001349289 (RefSeq) NM_001362360 (RefSeq)
	hsp70.3	ZDB-GENE-110713-1 (Zebrafish Model Organism Database) 30671 (Entrez Gene) hsp70.3 (Alliance of Genome Resources)	Chr3			NP_571472 (RefSeq) NM_131397 (RefSeq)
	hsp70l	ZDB-GENE-050321-1 (Zebrafish Model Organism Database) 560210 (Entrez Gene) hsp70l (Alliance of Genome Resources)	Chr8			NP_001107061 (RefSeq) NM_001113589 (RefSeq)
	hspa1b	ZDB-GENE-060503-867 (Zebrafish Model Organism Database) 798846 (Entrez Gene) hspa1b (Alliance of Genome Resources)	Chr8			NP_001093532 (RefSeq) NM_001100062 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.