Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PPP3CA	HGNC:9314 (HGNC) 5530 (Entrez Gene) 114105 (OMIM) PPP3CA (Alliance of Genome Resources)	Chr4 q24	Chr4:101023409-101348278 (-) GRCh38	developmental and epileptic encephalopathy 91	Q08209 (UniProt | EBI) NM_001130692 (RefSeq)
mouse	Ppp3ca	MGI:107164 (MGI) 19055 (Entrez Gene) Gene Tree Ppp3ca (Alliance of Genome Resources)	Chr3 63.34 cM	Chr3:136375885-136643488 (+) GRCm39	dilated cardiomyopathy	ENSMUSG00000028161 (Ensembl Gene Model) ENSMUSP00000053101 (Ensembl) ENSMUST00000056758 (Ensembl)
rat	Ppp3ca	RGD:3382 (Rat Genome Database) 24674 (Entrez Gene) Ppp3ca (Alliance of Genome Resources)	Chr2 q43			P63329 (UniProt | EBI) NM_017041 (RefSeq)
zebrafish	ppp3ca	ZDB-GENE-091113-24 (Zebrafish Model Organism Database) 794574 (Entrez Gene) ppp3ca (Alliance of Genome Resources)	Chr21			NP_001185479 (RefSeq) NM_001198550 (RefSeq)
	ppp3cb	ZDB-GENE-050417-406 (Zebrafish Model Organism Database) 550554 (Entrez Gene) ppp3cb (Alliance of Genome Resources)	Chr14			NP_001017856 (RefSeq) NM_001017856 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.