Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	KCNJ1	HGNC:6255 (HGNC) 3758 (Entrez Gene) 600359 (OMIM) KCNJ1 (Alliance of Genome Resources)	Chr11 q24.3	Chr11:128836315-128867373 (-) GRCh38	Bartter disease type 2	P48048 (UniProt | EBI) NM_153764 (RefSeq)
mouse	Kcnj1	MGI:1927248 (MGI) 56379 (Entrez Gene) Gene Tree Kcnj1 (Alliance of Genome Resources)	Chr9 17.69 cM	Chr9:32283789-32310493 (+) GRCm39	Bartter disease type 2	ENSMUSG00000041248 (Ensembl Gene Model) ENSMUSP00000131625 (Ensembl) ENSMUST00000172015 (Ensembl)
rat	Kcnj1	RGD:2957 (Rat Genome Database) 24521 (Entrez Gene) Kcnj1 (Alliance of Genome Resources)	Chr8 q21			P35560 (UniProt | EBI) NM_001309298 (RefSeq)
zebrafish	kcnj1a.1	ZDB-GENE-031118-55 (Zebrafish Model Organism Database) 386933 (Entrez Gene) kcnj1a.1 (Alliance of Genome Resources)	Chr18			NP_957329 (RefSeq) NM_201035 (RefSeq)
	kcnj1a.2	ZDB-GENE-050327-22 (Zebrafish Model Organism Database) 541499 (Entrez Gene) kcnj1a.2 (Alliance of Genome Resources)	Chr18			NP_001014334 (RefSeq) NM_001014312 (RefSeq)
	kcnj1a.3	ZDB-GENE-050420-256 (Zebrafish Model Organism Database) 569137 (Entrez Gene) kcnj1a.3 (Alliance of Genome Resources)	Chr18			NP_001038641 (RefSeq) NM_001045176 (RefSeq)
	kcnj1a.4	ZDB-GENE-050420-186 (Zebrafish Model Organism Database) 569191 (Entrez Gene) kcnj1a.4 (Alliance of Genome Resources)	Chr18			NP_001038643 (RefSeq) NM_001045178 (RefSeq)
	kcnj1a.5	ZDB-GENE-050420-120 (Zebrafish Model Organism Database) 568823 (Entrez Gene) kcnj1a.5 (Alliance of Genome Resources)	Chr18			NP_001038634 (RefSeq) NM_001045169 (RefSeq)
	kcnj1a.6	ZDB-GENE-050420-272 (Zebrafish Model Organism Database) 569052 (Entrez Gene) kcnj1a.6 (Alliance of Genome Resources)	Chr18			NP_001038640 (RefSeq) NM_001045175 (RefSeq)
	kcnj1b	ZDB-GENE-070620-9 (Zebrafish Model Organism Database) 556608 (Entrez Gene) kcnj1b (Alliance of Genome Resources)	Chr10			NP_001092204 (RefSeq) NM_001098734 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.