Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	FAT1	HGNC:3595 (HGNC) 2195 (Entrez Gene) 600976 (OMIM) FAT1 (Alliance of Genome Resources)	Chr4 q35.2	Chr4:186587794-186726722 (-) GRCh38	colorectal cancer esophagus squamous cell carcinoma lung non-small cell carcinoma lung small cell carcinoma oral squamous cell carcinoma	Q14517 (UniProt | EBI) NM_005245 (RefSeq)
mouse	Fat1	MGI:109168 (MGI) 14107 (Entrez Gene) Gene Tree Fat1 (Alliance of Genome Resources)	Chr8 24.81 cM	Chr8:45388484-45505294 (+) GRCm39	facioscapulohumeral muscular dystrophy nephrotic syndrome	ENSMUSG00000070047 (Ensembl Gene Model) ENSMUSP00000149194 (Ensembl) ENSMUST00000215588 (Ensembl)
rat	Fat1	RGD:621254 (Rat Genome Database) 83720 (Entrez Gene) Fat1 (Alliance of Genome Resources)	Chr16 q11			NP_114007 (RefSeq) NM_031819 (RefSeq)
zebrafish	fat1a	ZDB-GENE-050425-1 (Zebrafish Model Organism Database) 406172 (Entrez Gene) fat1a (Alliance of Genome Resources)	Chr1			NP_998132 (RefSeq) NM_212967 (RefSeq)
	fat1b	ZDB-GENE-130530-563 (Zebrafish Model Organism Database) 565591 (Entrez Gene) fat1b (Alliance of Genome Resources)	Chr14			XP_021328497 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.