Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MYOC	HGNC:7610 (HGNC) 4653 (Entrez Gene) 601652 (OMIM) MYOC (Alliance of Genome Resources)	Chr1 q24.3	Chr1:171635417-171652688 (-) GRCh38	juvenile glaucoma low tension glaucoma ocular hypertension open-angle glaucoma primary open angle glaucoma	Q99972 (UniProt | EBI) NM_000261 (RefSeq)
mouse	Myoc	MGI:1202864 (MGI) 17926 (Entrez Gene) Gene Tree Myoc (Alliance of Genome Resources)	Chr1 70.29 cM	Chr1:162466724-162477262 (+) GRCm39	open-angle glaucoma	ENSMUSG00000026697 (Ensembl Gene Model) ENSMUSP00000028020 (Ensembl) ENSMUST00000028020 (Ensembl)
rat	Myoc	RGD:620430 (Rat Genome Database) 81523 (Entrez Gene) Myoc (Alliance of Genome Resources)	Chr13 q22			Q9R1J4 (UniProt | EBI) NM_030865 (RefSeq)
zebrafish	myoc	ZDB-GENE-050425-2 (Zebrafish Model Organism Database) 548602 (Entrez Gene) myoc (Alliance of Genome Resources)	Chr20			NP_001015062 (RefSeq) NM_001015062 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.