Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ABCB11	HGNC:42 (HGNC) 8647 (Entrez Gene) 603201 (OMIM) ABCB11 (Alliance of Genome Resources)	Chr2 q31.1	Chr2:168915390-169031324 (-) GRCh38	benign recurrent intrahepatic cholestasis 2 intrahepatic cholestasis liver cirrhosis progressive familial intrahepatic cholestasis 2	O95342 (UniProt | EBI) NM_003742 (RefSeq)
mouse	Abcb11	MGI:1351619 (MGI) 27413 (Entrez Gene) Gene Tree Abcb11 (Alliance of Genome Resources)	Chr2 39.69 cM	Chr2:69068626-69172958 (-) GRCm39		ENSMUSG00000027048 (Ensembl Gene Model) ENSMUSP00000099771 (Ensembl) ENSMUST00000102710 (Ensembl)
rat	Abcb11	RGD:619930 (Rat Genome Database) 83569 (Entrez Gene) Abcb11 (Alliance of Genome Resources)	Chr3			O70127 (UniProt | EBI) NM_031760 (RefSeq)
zebrafish	abcb11a	ZDB-GENE-050517-13 (Zebrafish Model Organism Database) 797269 (Entrez Gene) abcb11a (Alliance of Genome Resources)	Chr9			XP_009303249 (RefSeq)
	abcb11b	ZDB-GENE-050517-14 (Zebrafish Model Organism Database) 571189 (Entrez Gene) abcb11b (Alliance of Genome Resources)	Chr11			XP_003199513 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.