Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NDUFS2	HGNC:7708 (HGNC) 4720 (Entrez Gene) 602985 (OMIM) NDUFS2 (Alliance of Genome Resources)	Chr1 q23.3	Chr1:161197104-161214723 (+) GRCh38	hypertrophic cardiomyopathy inherited metabolic disorder Leigh disease multiple sclerosis nuclear type mitochondrial complex I deficiency 6	O75306 (UniProt | EBI) NM_001166159 (RefSeq)
mouse	Ndufs2	MGI:2385112 (MGI) 226646 (Entrez Gene) Gene Tree Ndufs2 (Alliance of Genome Resources)	Chr1 79.25 cM	Chr1:171062426-171078956 (-) GRCm39		226646 (NCBI Gene Model) Q91WD5 (UniProt | EBI) NM_153064 (RefSeq)
rat	Ndufs2	RGD:1307109 (Rat Genome Database) 289218 (Entrez Gene) Ndufs2 (Alliance of Genome Resources)	Chr13 q24			Q641Y2 (UniProt | EBI) NM_001011907 (RefSeq)
zebrafish	ndufs2	ZDB-GENE-050522-273 (Zebrafish Model Organism Database) 553672 (Entrez Gene) ndufs2 (Alliance of Genome Resources)	Chr7			NP_001018481 (RefSeq) NM_001020645 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.