Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	AMACR	HGNC:451 (HGNC) 23600 (Entrez Gene) 604489 (OMIM) AMACR (Alliance of Genome Resources)	Chr5 p13.2	Chr5:33986165-34008104 (-) GRCh38	alpha-methylacyl-CoA racemase deficiency congenital bile acid synthesis defect 4 urinary bladder cancer	Q9UHK6 (UniProt | EBI) NM_014324 (RefSeq)
mouse	Amacr	MGI:1098273 (MGI) 17117 (Entrez Gene) Gene Tree Amacr (Alliance of Genome Resources)	Chr15 5.39 cM	Chr15:10981875-10995693 (+) GRCm39	alpha-methylacyl-CoA racemase deficiency	17117 (NCBI Gene Model) O09174 (UniProt | EBI) NR_177236 (RefSeq)
rat	Amacr	RGD:3048 (Rat Genome Database) 25284 (Entrez Gene) Amacr (Alliance of Genome Resources)	Chr2 q16			P70473 (UniProt | EBI) NM_012816 (RefSeq)
zebrafish	amacr	ZDB-GENE-050522-484 (Zebrafish Model Organism Database) 553653 (Entrez Gene) amacr (Alliance of Genome Resources)	Chr21			NP_001018462 (RefSeq) NM_001020626 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.