Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CYP2B6	HGNC:2615 (HGNC) 1555 (Entrez Gene) 123930 (OMIM) CYP2B6 (Alliance of Genome Resources)	Chr19 q13.2	Chr19:40991282-41018398 (+) GRCh38	acute myeloid leukemia drug dependence heroin dependence human immunodeficiency virus infectious disease neonatal abstinence syndrome nicotine dependence tuberculosis	P20813 (UniProt | EBI) NM_000767 (RefSeq)
mouse	Cyp2b23	MGI:3646735 (MGI) 243881 (Entrez Gene) Gene Tree Cyp2b23 (Alliance of Genome Resources)	Chr7 15.33 cM	Chr7:26364652-26385862 (-) GRCm39		ENSMUSG00000040650 (Ensembl Gene Model) ENSMUSP00000076578 (Ensembl) ENSMUST00000077356 (Ensembl)
rat	Cyp2b21	RGD:735174 (Rat Genome Database) 292728 (Entrez Gene) Cyp2b21 (Alliance of Genome Resources)	Chr1 q21			NP_942028 (RefSeq) NM_198733 (RefSeq)
zebrafish	cyp2y3	ZDB-GENE-050522-490 (Zebrafish Model Organism Database) 368352 (Entrez Gene) cyp2y3 (Alliance of Genome Resources)	Chr15			NP_001018658 (RefSeq) NM_001020822 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.