Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SPTLC1	HGNC:11277 (HGNC) 10558 (Entrez Gene) 605712 (OMIM) SPTLC1 (Alliance of Genome Resources)	Chr9 q22.31	Chr9:92000087-92115413 (-) GRCh38	hereditary sensory and autonomic neuropathy type 1A juvenile amyotrophic lateral sclerosis type 27	O15269 (UniProt | EBI) NM_001368272 (RefSeq)
mouse	Sptlc1	MGI:1099431 (MGI) 268656 (Entrez Gene) Gene Tree Sptlc1 (Alliance of Genome Resources)	Chr13 27.68 cM	Chr13:53486784-53531401 (-) GRCm39		268656 (NCBI Gene Model) O35704 (UniProt | EBI) NM_001426467 (RefSeq)
rat	Sptlc1	RGD:1307140 (Rat Genome Database) 361213 (Entrez Gene) Sptlc1 (Alliance of Genome Resources)	Chr17 p14			D4A2H2 (UniProt | EBI) NM_001108406 (RefSeq)
zebrafish	sptlc1	ZDB-GENE-050522-61 (Zebrafish Model Organism Database) 553981 (Entrez Gene) sptlc1 (Alliance of Genome Resources)	Chr10			NP_001018307 (RefSeq) NM_001020471 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.