Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MYH11	HGNC:7569 (HGNC) 4629 (Entrez Gene) 160745 (OMIM) MYH11 (Alliance of Genome Resources)	Chr16 p13.11	Chr16:15703135-15858438 (-) GRCh38	megacystis-microcolon-intestinal hypoperistalsis syndrome patent ductus arteriosus thoracic aortic aneurysm	P35749 (UniProt | EBI) NM_002474 (RefSeq)
mouse	Myh11	MGI:102643 (MGI) 17880 (Entrez Gene) Gene Tree Myh11 (Alliance of Genome Resources)	Chr16 9.71 cM	Chr16:14012392-14109227 (-) GRCm39		17880 (NCBI Gene Model) O08638 (UniProt | EBI) NM_001402796 (RefSeq)
rat	Myh11	RGD:3136 (Rat Genome Database) 24582 (Entrez Gene) Myh11 (Alliance of Genome Resources)	Chr10 q11			Q63862 (UniProt | EBI) NM_001429924 (RefSeq)
zebrafish	myh11a	ZDB-GENE-050531-1 (Zebrafish Model Organism Database) 554168 (Entrez Gene) myh11a (Alliance of Genome Resources)	Chr6			NP_001019619 (RefSeq) NM_001024448 (RefSeq)
	myh11b	ZDB-GENE-101124-2 (Zebrafish Model Organism Database) 566080 (Entrez Gene) myh11b (Alliance of Genome Resources)	Chr3			XP_017210292 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.