Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IL10RB	HGNC:5965 (HGNC) 3588 (Entrez Gene) 123889 (OMIM) IL10RB (Alliance of Genome Resources)	Chr21 q22.11	Chr21:33266367-33311420 (+) GRCh38	graft-versus-host disease hepatitis B inflammatory bowel disease 25	Q08334 (UniProt | EBI) NM_001405849 (RefSeq)
mouse	Il10rb	MGI:109380 (MGI) 16155 (Entrez Gene) Gene Tree Il10rb (Alliance of Genome Resources)	Chr16 52.87 cM	Chr16:91203166-91222718 (+) GRCm39		16155 (NCBI Gene Model) Q61190 (UniProt | EBI) NM_001405058 (RefSeq)
rat	Il10rb	RGD:1560373 (Rat Genome Database) 304091 (Entrez Gene) Il10rb (Alliance of Genome Resources)	Chr11 q11			NP_001100581 (RefSeq) NM_001107111 (RefSeq)
zebrafish	crfb4	ZDB-GENE-070905-3 (Zebrafish Model Organism Database) 797527 (Entrez Gene) crfb4 (Alliance of Genome Resources)	Chr9			NP_001077337 (RefSeq) NM_001083868 (RefSeq)
	il10rb	ZDB-GENE-050909-1 (Zebrafish Model Organism Database) 619391 (Entrez Gene) il10rb (Alliance of Genome Resources)	Chr9			NP_001029357 (RefSeq) NM_001034185 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.