Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TGFBR1	HGNC:11772 (HGNC) 7046 (Entrez Gene) 190181 (OMIM) TGFBR1 (Alliance of Genome Resources)	Chr9 q22.33	Chr9:99103647-99154192 (+) GRCh38	colorectal cancer Ferguson-Smith tumor Loeys-Dietz syndrome 1 Lynch syndrome pancreatic ductal adenocarcinoma urinary bladder cancer	P36897 (UniProt | EBI) NM_001306210 (RefSeq)
mouse	Tgfbr1	MGI:98728 (MGI) 21812 (Entrez Gene) Gene Tree Tgfbr1 (Alliance of Genome Resources)	Chr4 26.02 cM	Chr4:47353258-47414926 (+) GRCm39	Loeys-Dietz syndrome osteoarthritis systemic scleroderma	21812 (NCBI Gene Model) Q64729 (UniProt | EBI) NM_001429653 (RefSeq)
rat	Tgfbr1	RGD:3852 (Rat Genome Database) 29591 (Entrez Gene) Tgfbr1 (Alliance of Genome Resources)	Chr5 q22			P80204 (UniProt | EBI) NM_001429656 (RefSeq)
zebrafish	tgfbr1a	ZDB-GENE-051120-75 (Zebrafish Model Organism Database) 560578 (Entrez Gene) tgfbr1a (Alliance of Genome Resources)	Chr2			NP_001032772 (RefSeq) NM_001037683 (RefSeq)
	tgfbr1b	ZDB-GENE-091027-1 (Zebrafish Model Organism Database) 792928 (Entrez Gene) tgfbr1b (Alliance of Genome Resources)	Chr24			NP_001108531 (RefSeq) NM_001115059 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.