Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ACTN2	HGNC:164 (HGNC) 88 (Entrez Gene) 102573 (OMIM) ACTN2 (Alliance of Genome Resources)	Chr1 q43	Chr1:236664141-236764631 (+) GRCh38	arrhythmogenic right ventricular cardiomyopathy congenital myopathy 8 dilated cardiomyopathy 1AA	P35609 (UniProt | EBI) NM_001278343 (RefSeq)
mouse	Actn2	MGI:109192 (MGI) 11472 (Entrez Gene) Gene Tree Actn2 (Alliance of Genome Resources)	Chr13 4.54 cM	Chr13:12284312-12355613 (-) GRCm39		11472 (NCBI Gene Model) Q9JI91 (UniProt | EBI) NM_033268 (RefSeq)
rat	Actn2	RGD:1308097 (Rat Genome Database) 291245 (Entrez Gene) Actn2 (Alliance of Genome Resources)	Chr17 q12.1			NP_001163796 (RefSeq) NM_001170325 (RefSeq)
zebrafish	actn2b	ZDB-GENE-051127-39 (Zebrafish Model Organism Database) 641575 (Entrez Gene) actn2b (Alliance of Genome Resources)	Chr17			NP_001032662 (RefSeq) NM_001037573 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.