Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CACNA2D3	HGNC:15460 (HGNC) 55799 (Entrez Gene) 606399 (OMIM) CACNA2D3 (Alliance of Genome Resources)	Chr3 p21.1-p14.3	Chr3:54122552-55074557 (+) GRCh38		Q8IZS8 (UniProt | EBI) NM_018398 (RefSeq)
mouse	Cacna2d3	MGI:1338890 (MGI) 12294 (Entrez Gene) Gene Tree Cacna2d3 (Alliance of Genome Resources)	Chr14 16.8 cM	Chr14:28626900-29443821 (-) GRCm39		ENSMUSG00000021991 (Ensembl Gene Model) ENSMUSP00000022567 (Ensembl) ENSMUST00000022567 (Ensembl)
rat	Cacna2d3	RGD:631361 (Rat Genome Database) 306243 (Entrez Gene) Cacna2d3 (Alliance of Genome Resources)	Chr16 p16			Q8CFG5 (UniProt | EBI) NM_175595 (RefSeq)
zebrafish	cacna2d3	ZDB-GENE-030616-133 (Zebrafish Model Organism Database) 100148645 (Entrez Gene) cacna2d3 (Alliance of Genome Resources)	Chr11			XP_068080513 (RefSeq)
	cacna2d3a	ZDB-GENE-060328-4 (Zebrafish Model Organism Database) 100535196 (Entrez Gene) cacna2d3a (Alliance of Genome Resources)	Chr8			XP_021334188 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.