Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	EPS8L2	HGNC:21296 (HGNC) 64787 (Entrez Gene) 614988 (OMIM) EPS8L2 (Alliance of Genome Resources)	Chr11 p15.5	Chr11:694438-727727 (+) GRCh38	autosomal recessive nonsyndromic deafness 106	Q9H6S3 (UniProt | EBI) NM_022772 (RefSeq)
mouse	Eps8l2	MGI:2138828 (MGI) 98845 (Entrez Gene) Gene Tree Eps8l2 (Alliance of Genome Resources)	Chr7 86.66 cM	Chr7:140918824-140942933 (+) GRCm39		98845 (NCBI Gene Model) Q99K30 (UniProt | EBI) NM_133191 (RefSeq)
rat	Eps8l2	RGD:1310912 (Rat Genome Database) 361674 (Entrez Gene) Eps8l2 (Alliance of Genome Resources)	Chr1 q41			NP_001386596 (RefSeq) NM_001399667 (RefSeq)
zebrafish	eps8b	ZDB-GENE-060503-164 (Zebrafish Model Organism Database) 564779 (Entrez Gene) eps8b (Alliance of Genome Resources)	Chr18			XP_021323458 (RefSeq)
	eps8l2	ZDB-GENE-131121-340 (Zebrafish Model Organism Database) 798252 (Entrez Gene) eps8l2 (Alliance of Genome Resources)	Chr25			XP_021326269 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.