Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PLEKHG5	HGNC:29105 (HGNC) 57449 (Entrez Gene) 611101 (OMIM) PLEKHG5 (Alliance of Genome Resources)	Chr1 p36.31	Chr1:6467122-6520092 (-) GRCh38	autosomal recessive distal hereditary motor neuronopathy 4 Charcot-Marie-Tooth disease recessive intermediate C	O94827 (UniProt | EBI) NM_001042663 (RefSeq)
mouse	Plekhg5	MGI:2652860 (MGI) 269608 (Entrez Gene) Gene Tree Plekhg5 (Alliance of Genome Resources)	Chr4 82.86 cM	Chr4:152156955-152199857 (+) GRCm39		ENSMUSG00000039713 (Ensembl Gene Model) ENSMUSP00000158992 (Ensembl) ENSMUST00000239025 (Ensembl)
rat	Plekhg5	RGD:1303132 (Rat Genome Database) 310999 (Entrez Gene) Plekhg5 (Alliance of Genome Resources)	Chr5 q36			Q6RFZ7 (UniProt | EBI) NM_001415856 (RefSeq)
zebrafish	plekhg5a	ZDB-GENE-060503-766 (Zebrafish Model Organism Database) 562861 (Entrez Gene) plekhg5a (Alliance of Genome Resources)	Chr11			XP_009304323 (RefSeq)
	plekhg5b	ZDB-GENE-090908-6 (Zebrafish Model Organism Database) 796404 (Entrez Gene) plekhg5b (Alliance of Genome Resources)	Chr23			XP_017209178 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.