Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MEFV	HGNC:6998 (HGNC) 4210 (Entrez Gene) 608107 (OMIM) MEFV (Alliance of Genome Resources)	Chr16 p13.3	Chr16:3242027-3256633 (-) GRCh38	acute lymphoblastic leukemia acute myeloid leukemia asthma familial Mediterranean fever Henoch-Schoenlein purpura lung disease multiple myeloma myelodysplastic syndrome Sweet syndrome	O15553 (UniProt | EBI) NM_001198536 (RefSeq)
mouse	Mefv	MGI:1859396 (MGI) 54483 (Entrez Gene) Gene Tree Mefv (Alliance of Genome Resources)	Chr16 2.18 cM	Chr16:3525082-3535961 (-) GRCm39	familial Mediterranean fever	ENSMUSG00000022534 (Ensembl Gene Model) ENSMUSP00000097795 (Ensembl) ENSMUST00000100222 (Ensembl)
rat	Mefv	RGD:61889 (Rat Genome Database) 58923 (Entrez Gene) Mefv (Alliance of Genome Resources)	Chr10 q12			Q9JJ25 (UniProt | EBI) NM_031634 (RefSeq)
zebrafish	si:ch73-364h19.2	ZDB-GENE-131119-21 (Zebrafish Model Organism Database) 100537438 (Entrez Gene) si:ch73-364h19.2 (Alliance of Genome Resources)	ChrUN			XP_003198243 (RefSeq)
	si:ch211-114c12.5	ZDB-GENE-060526-13 (Zebrafish Model Organism Database) 565476 (Entrez Gene) si:ch211-114c12.5 (Alliance of Genome Resources)	Chr5			XP_068074327 (RefSeq)
	si:ch211-120g10.1	ZDB-GENE-130531-56 (Zebrafish Model Organism Database) 556805 (Entrez Gene) si:ch211-120g10.1 (Alliance of Genome Resources)	Chr3			XP_684799 (RefSeq)
	si:dkey-18p12.4	ZDB-GENE-070912-408 (Zebrafish Model Organism Database) 794946 (Entrez Gene) si:dkey-18p12.4 (Alliance of Genome Resources)	Chr9			NP_001116179 (RefSeq) NM_001122707 (RefSeq)
	si:dkey-219e21.2	ZDB-GENE-141215-26 (Zebrafish Model Organism Database) 797371 (Entrez Gene) si:dkey-219e21.2 (Alliance of Genome Resources)	Chr12			XP_021335987 (RefSeq)
	zgc:194990	ZDB-GENE-081022-171 (Zebrafish Model Organism Database) 568410 (Entrez Gene) zgc:194990 (Alliance of Genome Resources)	Chr8			NP_001124262 (RefSeq) NM_001130790 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.