Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SNAP25	HGNC:11132 (HGNC) 6616 (Entrez Gene) 600322 (OMIM) SNAP25 (Alliance of Genome Resources)	Chr20 p12.2	Chr20:10172395-10308258 (+) GRCh38	congenital myasthenic syndrome 18 Down syndrome	P60880 (UniProt | EBI) NM_003081 (RefSeq)
mouse	Snap25	MGI:98331 (MGI) 20614 (Entrez Gene) Gene Tree Snap25 (Alliance of Genome Resources)	Chr2 67.56 cM	Chr2:136555373-136624348 (+) GRCm39	attention deficit hyperactivity disorder obesity schizophrenia type 2 diabetes mellitus	ENSMUSG00000027273 (Ensembl Gene Model) ENSMUSP00000028727 (Ensembl) ENSMUST00000028727 (Ensembl)
rat	Snap25	RGD:3728 (Rat Genome Database) 25012 (Entrez Gene) Snap25 (Alliance of Genome Resources)	Chr3 q36			P60881 (UniProt | EBI) NM_030991 (RefSeq)
zebrafish	snap25a	ZDB-GENE-980526-468 (Zebrafish Model Organism Database) 30712 (Entrez Gene) snap25a (Alliance of Genome Resources)	Chr20			Q5TZ66 (UniProt | EBI) NM_131435 (RefSeq)
	snap25b	ZDB-GENE-980526-392 (Zebrafish Model Organism Database) 30711 (Entrez Gene) snap25b (Alliance of Genome Resources)	Chr17			Q6PC54 (UniProt | EBI) NM_131434 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.