Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MSH3	HGNC:7326 (HGNC) 4437 (Entrez Gene) 600887 (OMIM) MSH3 (Alliance of Genome Resources)	Chr5 q14.1	Chr5:80654652-80876815 (+) GRCh38	colorectal carcinoma endometrial cancer endometrial carcinoma familial adenomatous polyposis 4 lung non-small cell carcinoma	P20585 (UniProt | EBI) NM_002439 (RefSeq)
mouse	Msh3	MGI:109519 (MGI) 17686 (Entrez Gene) Gene Tree Msh3 (Alliance of Genome Resources)	Chr13 47.63 cM	Chr13:92348387-92491515 (-) GRCm39		17686 (NCBI Gene Model) P13705 (UniProt | EBI) NM_010829 (RefSeq)
rat	Msh3	RGD:1563954 (Rat Genome Database) 499505 (Entrez Gene) Msh3 (Alliance of Genome Resources)	Chr2 q12			NP_001178886 (RefSeq) NM_001191957 (RefSeq)
zebrafish	msh3	ZDB-GENE-060526-307 (Zebrafish Model Organism Database) 565400 (Entrez Gene) msh3 (Alliance of Genome Resources)	Chr5			NP_001103184 (RefSeq) NM_001109714 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.