Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IDUA	HGNC:5391 (HGNC) 3425 (Entrez Gene) 252800 (OMIM) IDUA (Alliance of Genome Resources)	Chr4 p16.3	Chr4:986997-1008351 (+) GRCh38	mucopolysaccharidosis I mucopolysaccharidosis Ih mucopolysaccharidosis Ih/s Scheie syndrome	P35475 (UniProt | EBI) NM_000203 (RefSeq)
mouse	Idua	MGI:96418 (MGI) 15932 (Entrez Gene) Gene Tree Idua (Alliance of Genome Resources)	Chr5 53.24 cM	Chr5:108808197-108832423 (+) GRCm39	mucopolysaccharidosis I otitis media	ENSMUSG00000033540 (Ensembl Gene Model) ENSMUSP00000108182 (Ensembl) ENSMUST00000112563 (Ensembl)
rat	Idua	RGD:1310943 (Rat Genome Database) 360904 (Entrez Gene) Idua (Alliance of Genome Resources)	Chr14 p22			NP_001165555 (RefSeq) NM_001172084 (RefSeq)
zebrafish	idua	ZDB-GENE-060526-29 (Zebrafish Model Organism Database) 567720 (Entrez Gene) idua (Alliance of Genome Resources)	Chr5			XP_001923689 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.