Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	COMP	HGNC:2227 (HGNC) 1311 (Entrez Gene) 600310 (OMIM) COMP (Alliance of Genome Resources)	Chr19 p13.11	Chr19:18782773-18791305 (-) GRCh38	carpal tunnel syndrome 2 multiple epiphyseal dysplasia 1 osteochondrodysplasia pseudoachondroplasia	P49747 (UniProt | EBI) NM_000095 (RefSeq)
mouse	Comp	MGI:88469 (MGI) 12845 (Entrez Gene) Gene Tree Comp (Alliance of Genome Resources)	Chr8 34.15 cM	Chr8:70826208-70834716 (+) GRCm39	multiple epiphyseal dysplasia pseudoachondroplasia	ENSMUSG00000031849 (Ensembl Gene Model) ENSMUSP00000003659 (Ensembl) ENSMUST00000003659 (Ensembl)
rat	Comp	RGD:2378 (Rat Genome Database) 25304 (Entrez Gene) Comp (Alliance of Genome Resources)	Chr16			P35444 (UniProt | EBI) NM_012834 (RefSeq)
zebrafish	comp	ZDB-GENE-060606-1 (Zebrafish Model Organism Database) 100318854 (Entrez Gene) comp (Alliance of Genome Resources)	Chr11			NP_001352232 (RefSeq) NM_001365303 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.