Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CYP24A1	HGNC:2602 (HGNC) 1591 (Entrez Gene) 126065 (OMIM) CYP24A1 (Alliance of Genome Resources)	Chr20 q13.2	Chr20:54143538-54173986 (-) GRCh38	colon cancer colorectal adenocarcinoma colorectal adenoma colorectal cancer esophagus squamous cell carcinoma hypercalcemia lung adenocarcinoma lung cancer lung carcinoma lung non-small cell carcinoma lung small cell carcinoma oral squamous cell carcinoma rectum cancer ulcerative colitis	Q07973 (UniProt | EBI) NM_001424341 (RefSeq)
mouse	Cyp24a1	MGI:88593 (MGI) 13081 (Entrez Gene) Gene Tree Cyp24a1 (Alliance of Genome Resources)	Chr2 91.91 cM	Chr2:170324877-170339065 (-) GRCm39		13081 (NCBI Gene Model) Q64441 (UniProt | EBI) NM_009996 (RefSeq)
rat	Cyp24a1	RGD:2462 (Rat Genome Database) 25279 (Entrez Gene) Cyp24a1 (Alliance of Genome Resources)	Chr3 q42			Q09128 (UniProt | EBI) NM_201635 (RefSeq)
zebrafish	cyp24a1	ZDB-GENE-060825-1 (Zebrafish Model Organism Database) 100004700 (Entrez Gene) cyp24a1 (Alliance of Genome Resources)	Chr6			NP_001082927 (RefSeq) NM_001089458 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.