Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ATP7A	HGNC:869 (HGNC) 538 (Entrez Gene) 300011 (OMIM) ATP7A (Alliance of Genome Resources)	ChrX q21.1	ChrX:77910690-78050395 (+) GRCh38	cutis laxa Menkes disease occipital horn syndrome X-linked distal spinal muscular atrophy 3	Q04656 (UniProt | EBI) NM_001282224 (RefSeq)
mouse	Atp7a	MGI:99400 (MGI) 11977 (Entrez Gene) Gene Tree Atp7a (Alliance of Genome Resources)	ChrX 47.36 cM	ChrX:105070882-105168532 (+) GRCm39	aortic aneurysm Menkes disease osteoarthritis X-linked distal spinal muscular atrophy 3	ENSMUSG00000033792 (Ensembl Gene Model) ENSMUSP00000058840 (Ensembl) ENSMUST00000055941 (Ensembl)
rat	Atp7a	RGD:2179 (Rat Genome Database) 24941 (Entrez Gene) Atp7a (Alliance of Genome Resources)	ChrX q22			P70705 (UniProt | EBI) NM_052803 (RefSeq)
zebrafish	atp7a	ZDB-GENE-060825-45 (Zebrafish Model Organism Database) 564924 (Entrez Gene) atp7a (Alliance of Genome Resources)	Chr14			NP_001036185 (RefSeq) NM_001042720 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.