Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CLDN23	HGNC:17591 (HGNC) 137075 (Entrez Gene) 609203 (OMIM) CLDN23 (Alliance of Genome Resources)	Chr8 p23.1	Chr8:8701937-8704096 (+) GRCh38		Q96B33 (UniProt | EBI) NM_194284 (RefSeq)
mouse	Cldn23	MGI:1919158 (MGI) 71908 (Entrez Gene) Gene Tree Cldn23 (Alliance of Genome Resources)	Chr8 21.21 cM	Chr8:36291866-36293713 (-) GRCm39		ENSMUSG00000055976 (Ensembl Gene Model) ENSMUSP00000049725 (Ensembl) ENSMUST00000060128 (Ensembl)
rat	Cldn23	RGD:1309001 (Rat Genome Database) 290789 (Entrez Gene) Cldn23 (Alliance of Genome Resources)	Chr16 q12.2			NP_001028234 (RefSeq) NM_001033062 (RefSeq)
zebrafish	cldn23.1	ZDB-GENE-091204-28 (Zebrafish Model Organism Database) 553515 (Entrez Gene) cldn23.1 (Alliance of Genome Resources)	Chr10			NP_001373643 (RefSeq) NM_001386714 (RefSeq)
	cldn23.2	ZDB-GENE-141216-471 (Zebrafish Model Organism Database) 567620 (Entrez Gene) cldn23.2 (Alliance of Genome Resources)	Chr10			XP_068080024 (RefSeq)
	cldn23l	ZDB-GENE-131127-551 (Zebrafish Model Organism Database) 794676 (Entrez Gene) cldn23l (Alliance of Genome Resources)	Chr17			XP_001333025 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.