Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MANF	HGNC:15461 (HGNC) 7873 (Entrez Gene) 601916 (OMIM) MANF (Alliance of Genome Resources)	Chr3 p21.2	Chr3:51385291-51389397 (+) GRCh38	breast cancer lung non-small cell carcinoma pancreatic cancer Parkinsonism renal cell carcinoma squamous cell carcinoma	P55145 (UniProt | EBI) NM_006010 (RefSeq)
mouse	Manf	MGI:1922090 (MGI) 74840 (Entrez Gene) Gene Tree Manf (Alliance of Genome Resources)	Chr9 57.98 cM	Chr9:106765952-106769137 (-) GRCm39		74840 (NCBI Gene Model) Q9CXI5 (UniProt | EBI) NM_029103 (RefSeq)
rat	Manf	RGD:1307252 (Rat Genome Database) 315989 (Entrez Gene) Manf (Alliance of Genome Resources)	Chr8 q32			P0C5H9 (UniProt | EBI) NM_001108183 (RefSeq)
zebrafish	manf	ZDB-GENE-060929-640 (Zebrafish Model Organism Database) 767691 (Entrez Gene) manf (Alliance of Genome Resources)	Chr22			NP_001070097 (RefSeq) NM_001076629 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.