Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SMC5	HGNC:20465 (HGNC) 23137 (Entrez Gene) 609386 (OMIM) SMC5 (Alliance of Genome Resources)	Chr9 q21.12	Chr9:70258978-70354873 (+) GRCh38	mosaic variegated aneuploidy syndrome	Q8IY18 (UniProt | EBI) NM_015110 (RefSeq)
mouse	Smc5	MGI:2385088 (MGI) 226026 (Entrez Gene) Gene Tree Smc5 (Alliance of Genome Resources)	Chr19 18.04 cM	Chr19:23183815-23251261 (-) GRCm39		ENSMUSG00000024943 (Ensembl Gene Model) ENSMUSP00000084837 (Ensembl) ENSMUST00000087556 (Ensembl)
rat	Smc5	RGD:1307492 (Rat Genome Database) 293967 (Entrez Gene) Smc5 (Alliance of Genome Resources)	Chr1 q51			NP_001099827 (RefSeq) NM_001106357 (RefSeq)
zebrafish	smc5	ZDB-GENE-061013-288 (Zebrafish Model Organism Database) 566749 (Entrez Gene) smc5 (Alliance of Genome Resources)	Chr10			E7F0W1 (UniProt | EBI) NM_001077572 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.