Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MYH7	HGNC:7577 (HGNC) 4625 (Entrez Gene) 160760 (OMIM) MYH7 (Alliance of Genome Resources)	Chr14 q11.2	Chr14:23412740-23435660 (-) GRCh38	autosomal dominant hyaline body myopathy autosomal recessive hyaline body myopathy cardiomyopathy congenital heart disease dilated cardiomyopathy dilated cardiomyopathy 1S distal myopathy 1 hypertrophic cardiomyopathy hypertrophic cardiomyopathy 1 hypoplastic left heart syndrome	P12883 (UniProt | EBI) NM_000257 (RefSeq)
mouse	Myh7	MGI:2155600 (MGI) 140781 (Entrez Gene) Gene Tree Myh7 (Alliance of Genome Resources)	Chr14 28.01 cM	Chr14:55208141-55232083 (-) GRCm39		140781 (NCBI Gene Model) Q91Z83 (UniProt | EBI) NM_001361607 (RefSeq)
rat	Myh7	RGD:62030 (Rat Genome Database) 29557 (Entrez Gene) Myh7 (Alliance of Genome Resources)	Chr15 p13			P02564 (UniProt | EBI) NM_017240 (RefSeq)
zebrafish	myh7	ZDB-GENE-991123-5 (Zebrafish Model Organism Database) 30616 (Entrez Gene) myh7 (Alliance of Genome Resources)	Chr2			NP_001106204 (RefSeq) NM_001112733 (RefSeq)
	myh7l	ZDB-GENE-061027-393 (Zebrafish Model Organism Database) 768300 (Entrez Gene) myh7l (Alliance of Genome Resources)	Chr2			NP_001070932 (RefSeq) NM_001077464 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.