Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	LARGE1	HGNC:6511 (HGNC) 9215 (Entrez Gene) 603590 (OMIM) LARGE1 (Alliance of Genome Resources)	Chr22 q12.3	Chr22:33066663-33922841 (-) GRCh38	congenital muscular dystrophy-dystroglycanopathy type A6 muscular dystrophy-dystroglycanopathy type B6	O95461 (UniProt | EBI) NM_001378624 (RefSeq)
mouse	Large1	MGI:1342270 (MGI) 16795 (Entrez Gene) Gene Tree Large1 (Alliance of Genome Resources)	Chr8 35.08 cM	Chr8:73541227-74080164 (-) GRCm39	facioscapulohumeral muscular dystrophy muscular dystrophy-dystroglycanopathy type B1 muscular dystrophy-dystroglycanopathy type B6	16795 (NCBI Gene Model) Q9Z1M7 (UniProt | EBI) NM_001317391 (RefSeq)
rat	Large1	RGD:1308895 (Rat Genome Database) 361368 (Entrez Gene) Large1 (Alliance of Genome Resources)	Chr19 p12-p11			NP_001416096 (RefSeq) NM_001429167 (RefSeq)
zebrafish	large1	ZDB-GENE-061204-1 (Zebrafish Model Organism Database) 446213 (Entrez Gene) large1 (Alliance of Genome Resources)	Chr4			Q66PG2 (UniProt | EBI) NM_001004537 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.