Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PDE8A	HGNC:8793 (HGNC) 5151 (Entrez Gene) 602972 (OMIM) PDE8A (Alliance of Genome Resources)	Chr15 q25.3	Chr15:84980440-85139145 (+) GRCh38		O60658 (UniProt | EBI) NM_173457 (RefSeq)
mouse	Pde8a	MGI:1277116 (MGI) 18584 (Entrez Gene) Gene Tree Pde8a (Alliance of Genome Resources)	Chr7 45.71 cM	Chr7:80863344-80984281 (+) GRCm39		ENSMUSG00000025584 (Ensembl Gene Model) ENSMUSP00000026672 (Ensembl) ENSMUST00000026672 (Ensembl)
rat	Pde8a	RGD:735125 (Rat Genome Database) 308776 (Entrez Gene) Pde8a (Alliance of Genome Resources)	Chr1 q31			NP_942062 (RefSeq) NM_198767 (RefSeq)
zebrafish	pde8a	ZDB-GENE-070112-622 (Zebrafish Model Organism Database) 791145 (Entrez Gene) pde8a (Alliance of Genome Resources)	Chr18			NP_001074096 (RefSeq) NM_001080627 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.