Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CCR5	HGNC:1606 (HGNC) 1234 (Entrez Gene) 601373 (OMIM) CCR5 (Alliance of Genome Resources)	Chr3 p21.31	Chr3:46370142-46376206 (+) GRCh38	asthma Behcet's disease berylliosis breast cancer cutaneous leishmaniasis fallopian tube disease gallbladder cancer granulomatosis with polyangiitis hepatitis B hepatitis C human immunodeficiency virus infectious disease hypertension juvenile rheumatoid arthritis Kawasaki disease multiple sclerosis posterior uveitis pulmonary sarcoidosis respiratory syncytial virus infectious disease rheumatoid arthritis sarcoidosis Sjogren's syndrome type 1 diabetes mellitus 22 urticaria West Nile fever	P51681 (UniProt | EBI) NM_001100168 (RefSeq)
mouse	Ccr5	MGI:107182 (MGI) 12774 (Entrez Gene) Gene Tree Ccr5 (Alliance of Genome Resources)	Chr9 75.05 cM	Chr9:123921557-123934153 (+) GRCm39	Coronavirus infectious disease	12774 (NCBI Gene Model) P51682 (UniProt | EBI) NM_009917 (RefSeq)
rat	Ccr5	RGD:620596 (Rat Genome Database) 117029 (Entrez Gene) Ccr5 (Alliance of Genome Resources)	Chr8 q32			O08556 (UniProt | EBI) NM_053960 (RefSeq)
zebrafish	cabz01093075.1	ZDB-GENE-160113-9 (Zebrafish Model Organism Database) 100329767 (Entrez Gene) cabz01093075.1 (Alliance of Genome Resources)	Chr16			XP_068070189 (RefSeq)
	ccr2	ZDB-GENE-151216-1 (Zebrafish Model Organism Database) 100004988 (Entrez Gene) ccr2 (Alliance of Genome Resources)	Chr16			XP_001344151 (RefSeq)
	ccr8.1	ZDB-GENE-070302-1 (Zebrafish Model Organism Database) 792495 (Entrez Gene) ccr8.1 (Alliance of Genome Resources)	Chr16			XP_009290350 (RefSeq)
	ccr11.1	ZDB-GENE-070302-5 (Zebrafish Model Organism Database) 100004625 (Entrez Gene) ccr11.1 (Alliance of Genome Resources)	Chr16			XP_068070164 (RefSeq)
	si:cabz01093077.1	ZDB-GENE-160113-45 (Zebrafish Model Organism Database) 100329837 (Entrez Gene) si:cabz01093077.1 (Alliance of Genome Resources)	Chr16			XP_005173521 (RefSeq)
	si:ch211-207g17.3	ZDB-GENE-160113-21 (Zebrafish Model Organism Database) 100005081 (Entrez Gene) si:ch211-207g17.3 (Alliance of Genome Resources)	Chr16			XP_001344220 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.