Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CTSB	HGNC:2527 (HGNC) 1508 (Entrez Gene) 116810 (OMIM) CTSB (Alliance of Genome Resources)	Chr8 p23.1	Chr8:11842524-11869533 (-) GRCh38	diabetes mellitus	P07858 (UniProt | EBI) NM_001908 (RefSeq)
mouse	Ctsb	MGI:88561 (MGI) 13030 (Entrez Gene) Gene Tree Ctsb (Alliance of Genome Resources)	Chr14 33.24 cM	Chr14:63359911-63383372 (+) GRCm39		13030 (NCBI Gene Model) P10605 (UniProt | EBI) NM_007798 (RefSeq)
rat	Ctsb	RGD:621509 (Rat Genome Database) 64529 (Entrez Gene) Ctsb (Alliance of Genome Resources)	Chr15 p12			P00787 (UniProt | EBI) NM_022597 (RefSeq)
zebrafish	ctsba	ZDB-GENE-040426-2650 (Zebrafish Model Organism Database) 406645 (Entrez Gene) ctsba (Alliance of Genome Resources)	Chr17			NP_998501 (RefSeq) NM_213336 (RefSeq)
	ctsbb	ZDB-GENE-070323-1 (Zebrafish Model Organism Database) 569298 (Entrez Gene) ctsbb (Alliance of Genome Resources)	Chr20			NP_001418075 (RefSeq) NM_001110478 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.