Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	BMPR2	HGNC:1078 (HGNC) 659 (Entrez Gene) 600799 (OMIM) BMPR2 (Alliance of Genome Resources)	Chr2 q33.1-q33.2	Chr2:202376327-202567751 (+) GRCh38	heart septal defect primary pulmonary hypertension pulmonary hypertension pulmonary venoocclusive disease 1	Q13873 (UniProt | EBI) NM_001204 (RefSeq)
mouse	Bmpr2	MGI:1095407 (MGI) 12168 (Entrez Gene) Gene Tree Bmpr2 (Alliance of Genome Resources)	Chr1 30.44 cM	Chr1:59802721-59917240 (+) GRCm39	primary pulmonary hypertension	12168 (NCBI Gene Model) O35607 (UniProt | EBI) NM_007561 (RefSeq)
rat	Bmpr2	RGD:71082 (Rat Genome Database) 140590 (Entrez Gene) Bmpr2 (Alliance of Genome Resources)	Chr9 q31			NP_536332 (RefSeq) NM_080407 (RefSeq)
zebrafish	bmpr2a	ZDB-GENE-070618-1 (Zebrafish Model Organism Database) 562822 (Entrez Gene) bmpr2a (Alliance of Genome Resources)	Chr6			NP_001034906 (RefSeq) NM_001039817 (RefSeq)
	bmpr2b	ZDB-GENE-070618-2 (Zebrafish Model Organism Database) 555655 (Entrez Gene) bmpr2b (Alliance of Genome Resources)	Chr9			NP_001034896 (RefSeq) NM_001039807 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.