Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NPPC	HGNC:7941 (HGNC) 4880 (Entrez Gene) 600296 (OMIM) NPPC (Alliance of Genome Resources)	Chr2 q37.1	Chr2:231921809-231926396 (-) GRCh38	depressive disorder hypertension	P23582 (UniProt | EBI) NM_024409 (RefSeq)
mouse	Nppc	MGI:97369 (MGI) 18159 (Entrez Gene) Gene Tree Nppc (Alliance of Genome Resources)	Chr1 43.98 cM	Chr1:86594015-86598295 (-) GRCm39	achondroplasia osteochondrodysplasia	18159 (NCBI Gene Model) Q61839 (UniProt | EBI) NM_010933 (RefSeq)
rat	Nppc	RGD:620850 (Rat Genome Database) 114593 (Entrez Gene) Nppc (Alliance of Genome Resources)	Chr9 q35			P55207 (UniProt | EBI) NM_053750 (RefSeq)
zebrafish	nppc	ZDB-GENE-070705-24 (Zebrafish Model Organism Database) 570244 (Entrez Gene) nppc (Alliance of Genome Resources)	Chr22			NP_001103410 (RefSeq) NM_001109940 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.